
Laboratory of Reproductive Medicine
Lab Events
Weekend School of Applied Embryology, 2025

Summer School of Applied Embryology, 2024
News
Research Projects
Epigenetics
Histone deacetylase SIRT1 regulates early embryonic development through the epigenetic and non-epigenetic modes of action.
The most recent paper about SIRT1 across mammalian species: Nevoral et al., 2024
Cooperating partners in France and Slovakia
Hydrogen sulfide
This gasotransmitter acts as a second messenger, modifying proteins post-translationally, particularly in transcriptionally silenced gametes.
We have recognized hydrogen sulfide signal molecule modulating sperm surface signature: Řimnáčová et al., 2022
Cooperating partners in Spain and South Korea
Mitochondria
Oocytes carry a cytoplasmic genome housed in mitochondrial DNA, silenced till the late blastocyst.
We presented the idea of risky transmission of mitochondrial mutations to offspring: Shavit et al., 2023
Partners in USA
Contact
Our Team
- Jan NEVORAL, Ph.D., group leader
- Miki SHAVIT, graduate student
- Kateřina GRYGAROVÁ, graduate student
- Věra VTÍPILOVÁ, graduate student
- Gabriela PŘIBÁŇOVÁ, technician
- Eva KRALOVCOVÁ, technician
- Václav RÚČKA, technician
- Kristýna POPELKOVÁ, technician
- Štěpánka JANSOVÁ, technician